Treating Canine Lymphoma in General Practice
Canine lymphoma is one of the most common, and best documented, neoplasms
in veterinary medicine with many patients managed in general practice. Lymphoma
is generally very sensitive to chemotherapy and a rewarding disease to treat.
Whilst the diagnosis can often be established cytologically, histological assessment
provides further classification. Immunophenotyping (to characterise disease as of
B or T cell origin) is recommended and can be achieved via immunohistochemistry,
flow cytometry or PCR for antigen rearrangement (PARR). Ideally, staging should
be performed at the time of the initial diagnosis and should include thoracic and
abdominal imaging as well as bone marrow assessment. There are many different
types of lymphoma with different clinical courses and variable prognoses so initial
characterisation of each individual case is essential in guiding the treatment plan.
High grade B cell multicentric lymphoma is most commonly encountered and has
an expected survival time of 10 to 12 months when treated with chemotherapy.
Multidrug chemotherapy protocols are the mainstay of treatment and CHOP and
LOPP regimens are recommended as first-line treatment for high grade multicentric
lymphoma. However, many alternative protocols are available and can be used to
overcome any time and financial constraints the client might have.
All our Tutored Online CPD Courses are written and taught by an expert in the relevant field. The tutor for this course is:
Isabelle Desmas-Bazelle DVM MVetMed MRCVS DipAVCIM (Onc) American Specialist in Veterinary Oncology